DESIGN, FORMULATION, AND CHARACTERIZATION OF LIPOSOMAL-ENCAPSULATED GEL FOR TRANSDERMAL DELIVERY OF FLUCONAZOLE
نویسندگان
چکیده
منابع مشابه
Formulation and characterization of alprazolam transdermal gel based on nanoliposomes
Background: Nowadays transdermal drug delivery systems (TDDS), as an appropriate replacement for oral and parenteral dosage forms, are developing. These systems which designed to transport drugs through skin layers into the systemic circulation, have several benefits such as avoiding first-pass metabolism, sustained and controlled drug release, reducing side effects, and ease of use. The aim of...
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Celecoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, joint inflammation and sport injuries. Long term administration of the drug results in such complications as gastrointestinaland renal disturbances and cardio-vascular complications. The main objective of the present study was to investigate the feasibility of delivering celecoxib incorporated in gel formula...
متن کاملtransdermal iontophoretic delivery of celecoxib from gel formulation
celecoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, joint inflammation and sport injuries. long term administration of the drug results in such complications as gastrointestinaland renal disturbances and cardio-vascular complications. the main objective of the present study was to investigate the feasibility of delivering celecoxib incorporated in gel formula...
متن کاملformulation and evaluation of liposomes for transdermal delivery of celecoxib
materials and methods liposomes were prepared by thin film method using soya lecithin and cholesterol. physicochemical characteristics of the liposomes such as, particle size, drug encapsulation efficiency were determined. also, drug release and in vitro skin permeability through rat skin were evaluated using franz diffusion cells. results the results showed that the maximum drug encapsulation ...
متن کاملComparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery
BACKGROUND The purpose of this study was to determine the most appropriate dialysis equilibrium method to assess liposomal gel formulations containing hydrophobic drugs, to give the most accurate indication of drug release. METHODS Loperamide hydrochloride-encapsulated liposomes, composed of L-α-phosphatidylcholine and cholesterol (molar ratio of 2:1), were prepared according to the method of...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2018
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2018.v11i8.25621